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Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10) Peptid

SIGLEC10 Reaktivität: Säugetier Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN937100

Kurzübersicht für Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10) Peptid (ABIN937100)

Target

SIGLEC10 (Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10))

Spezies

Säugetier

Quelle

  • 2
Synthetic

Applikation

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Protein-Typ

    Synthetic

    Sequenz

    CHVDFSRKGV SAQRTVRLRV AYAPRDLVIS ISRDNTPALE PQPQGNVPYL

    Produktmerkmale

    A synthetic peptide for use as a blocking control in assays to test for specificity of SIGLEC10 antibody,
    Alternative Names: SIGLEC10 control peptide, SIGLEC10 antibody Blocking Peptide, Anti-SIGLEC10 Blocking Peptide, Sialic Acid Binding Ig-Like Lectin 10 Blocking Peptide, MGC126774 Blocking Peptide, PRO940 Blocking Peptide, SIGLEC-10 Blocking Peptide, SLG2 Blocking Peptide, SIGLEC10, SIGLEC-10, SIGLEC 10, SIGLEC-10 Blocking Peptide, SIGLEC 10 Blocking Peptide
  • Applikationshinweise

    Optimal conditions should be determined by the investigator

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Handhabung

    Avoid repeated freeze/thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20 °C long term.
  • Target

    SIGLEC10 (Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10))

    Hintergrund

    SIGLEC10 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. SIGLEC10 preferentially binds to alpha-2,3- or alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, SIGLEC10 may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules.

    Molekulargewicht

    76 kDa
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